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Triomune (Nevirapine)
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Triomune

Triomune belongs to the class of antiretroviral medications called non-nucleoside reverse transcriptase inhibitors (NNRTIs). It is used in combination with other antiretroviral medications to treat the infection caused by the human immunodeficiency virus (HIV).

Other names for this medication:
Cytocom, Duovir, Emduo, Emtri, Lamostad, Lazid, Nevilast, Nevimune, Nevipan, Nevir, Nevirapine, Neviraprine, Neviretro, Nevirex, Nevivir, Nexvir, Stavex, Trimune, Triomune, Trivir, Virocomb, Virolans, Zidolam

Similar Products:
Zetia, Detrol, Nimotop, Lipitor, Zovirax, Amethopterin, Sildigra, Temovate, Kemadrin, Alphadol, Vitalpha, Osactin, Fludizol, Ramicard, Addyi, Beten, Osteobel,

Also known as: Nevirapine

Description

Triomune XR is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Triomune XR is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, and should not be used to prevent HIV.

Triomune XR oral solution (liquid) is for use in adults and children as young as 15 days old. This medicine extended-release tablets are for use in adults and children who are at least 6 years old.

Dosage

This section provides information on the proper use of a number of products that contain nevirapine. It may not be specific to Triomune O/S. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change the dose or stop using this medicine without checking first with your doctor. When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine.

This medicine comes with a Medication Guide. Read and follow these instructions carefully before starting nevirapine treatment and each time you refill your prescription. Ask your doctor if you have any questions.

Nevirapine may be taken with or without food, and with water, milk, or soda.

If you or your child are taking the oral liquid, shake it gently before use. Use an oral dosing syringe or dosing cup to measure the right dose. After drinking the medicine, rinse the dosing cup with water and drink the water to make sure you get all of the medicine. If your dose is less than 5 mL (one teaspoonful), use the dosing syringe.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

Keep taking nevirapine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

It is important to take nevirapine as part of a combination treatment. Take all other medicines your doctor has prescribed at the right time of the day. This will make your medicines work better.

This medicine works best when there is a constant amount in the blood. To help keep blood levels constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. For example, if you or your child are taking one dose per day, try to take it at the same time each day. If you are taking two doses per day, the doses should be spaced about 12 hours apart. If you need help planning the best times to take your medicine, check with your doctor.

Do not take more than one dosage form of nevirapine at the same time. Talk to your doctor if you have any questions.

If you stop taking this medicine for more than 7 days, ask your doctor how much to use before you start taking it again. .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of HIV infection: For oral dosage form (extended-release tablets): Adults—At first, one 200 milligram (mg) Triomune® immediate-release tablet once a day for the first 14 days. This is followed by one 400 mg Triomune XR® tablet once a day, together with other HIV medicines. Children 6 to 17 years of age with a body surface area of 1.17 square meter (m2) or greater—Dose is based on body size and must be determined by your doctor. The starting dose is usually 150 milligrams (mg) per square meter (m2) of Triomune® oral suspension or tablets for the first 14 days. This is followed by 400 mg of Triomune XR® once a day, together with other HIV medicines. Children younger than 6 years of age with a body surface area of less than 1.17 m2—Use is not recommended. For oral dosage forms (suspension or tablets): Adults—200 milligrams (mg) once a day for 2 weeks, followed by 200 mg 2 times per day, together with other medicines. Children and infants 15 days of age and older—Dose is based on body size and must be determined by your doctor. Infants younger than 15 days of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store Triomune tablets or oral powder at room temperature between 68-77 degrees F (20-25 degrees C). Keep Triomune in the original container. Do not use Triomune if the seal over the bottle opening is broken or missing. Keep the bottle tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Triomune are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use this medicine if you are allergic to Triomune, or if you have moderate to severe liver disease.

Some medicines can interact with Triomune and should not be used at the same time. Your doctor may need to change your treatment plan if you use any of the following drugs:

atazanavir; delavirdine; etravirine; itraconazole; ketoconazole; rifampin; rilpivirine; St. John's wort; or telaprevir.

To make sure Triomune is safe for you, tell your doctor if you have:

skin problems; liver disease (or a history of hepatitis or cirrhosis); kidney disease (or if you are on dialysis); or if you have ever taken delavirdine or efavirenz and they were not effective in treating your condition.

It is not known whether this medicine will harm an unborn baby. However, Triomune may be more likely to cause liver damage in a pregnant woman. Tell your doctor if you are pregnant or plan to become pregnant. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of nevirapine on the baby.

Triomune can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Do not give this medicine to a child without medical advice.

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