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Cvate (Clobetasol)

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Cvate is a very strong corticosteroid. It helps treat flare-ups of skin conditions like psoriasis by lessening inflammation in the body and calming down the immune system.

Other names for this medication:
Betalic, Clobadis, Clobesym, Clobetamil, Clobetasol, Clobquad, Clomad, Clomic, Clonate, Cloriv, Clotof, Cortaz, Cosvate, Covate, Cutivate, Cvate, Embeline, Etavone, Hinate, Kloryl, Klosol, Lobate, Sonaderm, Taxalic, Tenovate, Tigerderm, Topifort, Zincoderm

Similar Products:
Cycrin, Dramamine, Elavil, Celebrex, Zyloprim, Glucotrol, Zanaflex, Zofran, Olorest, Lezest, Azpax, Raitrip, Ofena, Stafcure,

Also known as: Clobetasol


Clobetasol topical is used to help relieve redness, itching, swelling, or other discomfort caused by certain skin conditions. The solution is used for scalp problems, the foam is used for mild to moderate plaque psoriasis, the cream, lotion, and spray are used for moderate to severe plaque psoriasis, and the foam and shampoo are used for moderate to severe scalp psoriasis. This medicine is a corticosteroid (cortisone-like medicine or steroid).

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain clobetasol. It may not be specific to Cvate E. Please read with care.

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

This medicine is for use on the skin only. Do not get it into your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin or scalp problem completely, it is very important that you keep using this medicine for the full time of treatment. Do not miss any doses.

This medicine should only be used for skin conditions that your doctor is treating. Check with your doctor first before using it for other conditions, especially if you think that a skin infection may be present. This medicine should not be used to treat certain kinds of skin infections or conditions, such as severe burns.

Do not use this medicine on the face, groin, or underarms, or if you have skin thinning, unless directed to do so by your doctor.

To use the cream, foam, gel, lotion, ointment, or spray:

Wash your hands with soap and water before and after using this medicine. Apply or spray a thin layer of this medicine to the affected area of the skin. Rub it in gently. With the lotion, protect the skin from water, clothing, or anything that causes rubbing until the medicine has dried. Also, shake the lotion well before using it. With the foam, do not dispense directly from the can into your hands, unless the hands are the affected area. Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor. Do not use Clobex® spray or Impoyz™ cream for more than 2 weeks unless your doctor told you to.

To use the foam, scalp solution, or shampoo:

Wash your hands with soap and water before and after using this medicine. Apply a thin layer of this medicine to the affected area of the scalp. Rub it in gently. Do not cover the scalp (eg, shower cap, bathing cap) while it is being treated. With the shampoo, do not wet your hair before using it. And if the shampoo gets on any part of your body other than your scalp, rinse the area well with water. Do not use the shampoo for more than 4 weeks, and the foam and scalp solution for more than 2 weeks unless your doctor told you to.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For redness, itching, and swelling of the skin: For topical dosage forms (cream, gel, or ointment): Adults—Apply to the affected area of the skin 2 times per day. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 12 years of age—Use is not recommended. For topical dosage form (lotion): Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. For plaque psoriasis: For topical dosage form (cream): Impoyz™: Adults—Apply to the affected area of the skin 2 times per day. Children—Use is not recommended. Cvate®: Adults and children older than 16 years of age—Apply to the affected area of the skin 2 times per day. Children younger than 16 years of age—Use is not recommended. For topical dosage form (foam): Adults—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the skin 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (spray): Adults—Spray directly to the affected area of the skin 2 times per day. Children—Use is not recommended. For scalp problems: For topical dosage forms (foam or scalp solution): Adults—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children 12 to 17 years of age—Apply to the affected area of the scalp 2 times per day, once in the morning and once at night. Children younger than 12 years of age—Use is not recommended. For topical dosage form (shampoo): Adults—Apply to the affected area of the scalp once a day. Children—Use is not recommended.


Generic Cvate is not expected to cause overdose symptoms. But long-term use of high Generic Cvate doses can lead to symptoms such as: thinning skin, easy bruising, changes in the shape or location of body fat (especially in your face, neck, back, and waist), increased acne or facial hair, menstrual problems, impotence, or loss of interest in sex.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the foam can or spray bottle at room temperature, away from heat, flames, smoke, and direct light. Do not keep this medicine inside a car where it could be exposed to extreme heat. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store the Cvate® E cream at room temperature, away from heat, moisture, and direct light. Do not refrigerate. Keep Cvate® E cream and Impoyz™cream from freezing.

Detailed Cvate E dosage information

Side effects

The most common side effects associated with Cvate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Cvate if you are allergic to it.

Tell your doctor if you have ever had:

any type of skin infection; a skin reaction to any steroid medicine; liver disease; or an adrenal gland disorder.

Steroid medicines can increase the glucose (sugar) levels in your blood or urine. Tell your doctor if you have diabetes.

It is not known whether Cvate will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk. If you apply clobetasol to your chest, avoid areas that may come into contact with the baby's mouth.

Cvate is not approved for use by anyone younger than 12 years old. Some brands or forms of this medicine are for use only in adults 18 and over.

Children can absorb larger amounts of this medicine through the skin and may be more likely to have side effects.

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Using gene-specific oligonucleotide probes, the expression of four pregnancy specific beta 1 glycoprotein (PSG) genes termed A, B, C-D and E (Streydio et al., 1988 and in press) and of some of their splice variants Ci, C and D were analysed during human placental development. The surgical significance of splenoportography in portal hypertension. A questionnaire among 3,956 men and women aged 24-65 years in Vejle County, Slangerup and Helsinge municipalities. Similarly, CBX or 3-MA restored long-term potentiation (LTP), relative to TBI hippocampal slices. The use of 40 nm Pd cubes as cores gave uniform and size-tunable Pd-Cu2O nanocubes and truncated octahedra that display the Pd SPR band. Administration of the BET protein inhibitor RVX-208 showed no greater increase in apoA-I or HDL-C or incremental regression of atherosclerosis than administration of placebo. The theoretical formalisms behind each method is explained highlighting its strengths as well as its limitations, followed by a description of a number of case studies for each method.

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Donor and recipient determinants of fatal and nonfatal cardiac dysfunction during the first week after orthotopic heart transplantation. Fetal pyelectasis and Down syndrome: is genetic amniocentesis warranted?. The mean weight reduction obtained was 1.4 g on average (SD 0.599), with values between 0.5 and 2.6 grams. Injection of inositol 1,4,5 trisphosphate (InsP3) into Limulus ventral photoreceptors elevates the concentration of intracellular calcium ions and as a consequence depolarizes the photoreceptor. Synthesis of novel photofunctional multinuclear complexes using a coupling reaction. Included were all patients with biliary tract injuries who underwent biliary reconstruction and liver biopsy. A constantly high pharmaceutical quality is required to avoid therapeutic risks. A novel adsorbent was prepared via crosslinking graft copolymerization of 2-(dimethylamino) ethyl methacrylate (DMAEMA) onto carboxymethyl cellulose (CMC) backbone.

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