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Cleft (Leflunomide)
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Cleft

Cleft is in a class of medications called disease-modifying antirheumatic drugs (DMARDs). It works by decreasing inflammation and slowing the progress of the condition, which can help improve the physical activity of people with rheumatoid arthritis.

Other names for this medication:
Cleft, Feluno, Leflunomide, Lefno, Lefra, Lefuma, Lefumide, Lisifen, Rumalef

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Also known as: Leflunomide

Description

Cleft (leflunomide) affects the immune system and reduces swelling and inflammation in the body.

Cleft is used to treat the symptoms of rheumatoid arthritis.

Dosage

Usual Adult Dose for Rheumatoid Arthritis:

Loading dose: 100 mg orally once a day for 3 days Maintenance: 20 mg orally once a day (If not well tolerated, the dose may be decreased to 10 mg orally once a day) Comment: -Hematology parameters and liver enzymes should be monitored. Use: For the treatment of active rheumatoid arthritis (RA): -To reduce signs and symptoms -To inhibit structural damage as evidenced by X-ray erosions and joint space narrowing -To improve physical function

Detailed Cleft dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include diarrhea, stomach pain, pale skin, easy bruising or bleeding, dark urine, or jaundice (yellowing of the skin or eyes).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cleft are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using Cleft, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

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